Publications by authors named "Zachary Slama"
Article Synopsis
- Calprotectin (S100A8/A9) acts as a tumor suppressor in head and neck squamous cell carcinoma (HNSCC), with its levels correlating to patient survival rates.
- The research aims to assess changes in S100A8/A9 as oral carcinogenesis progresses and its regulatory role on the epidermal growth factor receptor (EGFR) in HNSCC.
- Results indicate that S100A8/A9 expression decreases with cancer progression and is inversely related to EGFR levels, suggesting that lower calprotectin may lead to increased EGFR and reduced apoptosis, impacting patient outcomes.
Solitary oral epidermolytic acanthoma: Case report of a rarely diagnosed entity.
Oral Surg Oral Med Oral Pathol Oral Radiol
December 2019
Article Synopsis
- - Epidermolytic acanthoma is a rare skin condition that typically looks warty and often appears on the genital skin, but in this case, it was found in the mouth of a 71-year-old man.
- - The oral lesion measured 2 mm, was well-defined, and showed specific microscopic features like hyperkeratosis and certain types of cell degeneration.
- - No HPV was detected, and there are few documented cases linking this condition to serious oral health issues, making it important to consider in diagnosing similar benign lesions in the mouth.
Directed cell migration by contact guidance in aligned collagenous extracellular matrix (ECM) is a critical enabler of breast cancer dissemination. The mechanisms of this process are poorly understood, particularly in 3D, in part because of the lack of efficient methods to generate aligned collagen matrices. To address this technological gap, we propose a simple method to align collagen gels using guided cellular compaction.
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