Does Intravenous Lactated Ringer's Solution Raise Serum Lactate?

Background: Serum lactate increases in states of severe sepsis and shock, but its interpretation may be subject to confounders. Lactated Ringer's solution (LR) is used in the resuscitation of septic patients and contains 28 mmol/L of sodium lactate.

Objectives: We sought to determine if a bolus of 30 mL/kg of LR increases serum lactate levels.