Publications by authors named "Zachary S Sacks"

Selective laser trabeculoplasty (SLT), used to treat glaucoma and ocular hypertension, requires the use of a gonioscope placed on the cornea to visualize and irradiate the trabecular meshwork (TM). Alternatively, non-contact direct SLT (DSLT) irradiates the TM through the overlying tissues. Here we analyze this innovative procedure using analytical modeling and Monte Carlo simulations to quantify the laser energy reaching the TM through the overlying tissues.

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Article Synopsis
  • About 105 million people globally have glaucoma, often leading to blindness, and current surgical methods struggle due to tissue scarring.
  • A femtosecond laser operating at 1,700 nm was tested to create precise incisions in human sclera, addressing the issues with previous shorter wavelength techniques.
  • Results showed that this method effectively produced narrow subsurface cuts without damaging surrounding tissue, suggesting future in vivo studies are needed to explore its surgical potential.
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Background And Objectives: Femtosecond pulses can generate high precision subsurface photodisruption in transparent tissues, such as the cornea. We used femtosecond laser technology to demonstrate early proof of concept for high precision subsurface photodisruption in the translucent sclera. This technique may ultimately enable novel surgical procedures for the treatment of glaucoma and/or presbyopia.

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