Publications by authors named "Zachary Henig"
J Neuroendocrinol
November 2024
Article Synopsis
- Cushing's syndrome (CS) has significant neurocognitive and psychiatric impacts that reduce quality of life, prompting a systematic review of affected patients compared to healthy controls and those with non-functioning pituitary adenomas (NFPA).
- The study analyzed 40 eligible research papers, identifying 2603 participants, 45.2% of whom had Cushing's disease (CD), with a focus on their psychiatric symptoms and cognitive performance before and after surgical treatment.
- Findings indicate that higher baseline cortisol levels in patients with CS correlate with worse cognitive function, even post-surgery, and prolonged periods of uncontrolled CS may lead to persistent cognitive challenges.
