Synopsis of recent research by authors named "Zachary Graham"
- Zachary Graham's research primarily focuses on the pharmacological effects and mechanisms of boldine, an alkaloid derived from the Chilean Boldo tree, highlighting its neuroprotective, anti-inflammatory, and anticancer properties, particularly via the blockade of connexin hemichannels in models of spinal cord injury and other diseases.
- Additional studies investigate the metabolic responses and adaptations in human skeletal muscle during various exercise regimens, alongside the distinct molecular changes associated with muscle wasting and recovery, particularly among older adults and in the context of total hip arthroplasty.
- Graham's work employs advanced methodologies, including serum metabolomics and multi-omics profiling, to elucidate the molecular underpinnings of muscle health and disease, paving the way for potential therapeutic strategies to mitigate muscle atrophy and improve recovery outcomes.
