EUS-guided rendezvous technique for pancreas divisum.

Video 1EUS-guided rendezvous technique for pancreas divisum.

Rising Rate of Obesity in Patients Admitted for Crohn's Disease Increases Costs But Not Mortality.

Goal: The goal of this study was to compare outcomes and trends for inpatients with Crohn's disease (CD) and obesity.

Background: Obesity is a growing concern in the United States. Current data on the effect of obesity on the course of the CD are conflicted.

Out of Sight-Out of Mind: Impact of Cascade Reporting on Antimicrobial Usage.

Background: There is a paucity of data evaluating the strategy of suppressing broader-spectrum antibiotic susceptibilities on utilization. Cascade reporting (CR) is a strategy of reporting antimicrobial susceptibility test results in which secondary (eg, broader-spectrum, costlier) agents may only be reported if an organism is resistant to primary agents within a particular drug class. Our objective was to evaluate the impact of ceftriaxone-based cascade reporting on utilization of cefepime and clinical outcomes in patients with ceftriaxone-susceptible and clinical cultures.

A Multicenter Study Into Causes of Severe Acute Liver Injury.

The differential diagnosis of an increase in alanine aminotransferase (ALT) level and/or aspartate aminotransferase (AST) level of ≥1000 IU/L often is stated to include 3 main etiologies: ischemic hepatitis, acute viral hepatitis (typically hepatitis A and hepatitis B), and drug-induced (more specifically, acetaminophen/paracetamol) liver injury (DILI). Unfortunately, there are a paucity of studies examining the most common causes of acute liver injury (ALI) and those that have been published have been small, single-center, or examined less severe increases in ALT or AST levels. We conducted a multicenter study of all patients with an ALT and/or AST level ≥1000 IU/L.