Publications by authors named "Zachary Arnold"

The obesity rate is increasing worldwide despite various policies and efforts. However, there is a concern with underrecording and underreporting of obesity in outpatient and inpatient settings which can affect patient care. Local and national reports based on medical records can provide an underestimated rate of obesity.

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Purpose: Restricted and/or repetitive displays of behavior, interests, or activities (RRBs) are one of the core symptom domains of autism spectrum disorder (ASD). Current and past research indicates two 'clusters' of RRBs in children with ASD: repetitive sensorimotor (e.g.

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Landfills provide seasonally reliable food resources to many bird species, including those perceived to be pest or invasive species. However, landfills often contain multiple habitat types that could attract diverse species, including those of conservation concern. To date, little is known about the characteristics and composition of bird communities at landfills relative to local and regional pools.

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Background: Intervention during the first years of life for children with autism spectrum disorder (ASD) may have the strongest impact on long-term brain development and functioning. Yet, barriers such as a shortage of trained professionals contribute to significant delays in service. The goal of this proof-of-concept study was to explore strategies that support timely and equitable deployment of ASD-specific interventions.

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Article Synopsis
  • Canonical pre-mRNA splicing typically requires certain proteins (snRNPs) to remove long introns, but non-canonical splicing has been observed for some short introns in tRNAs and mRNAs, like XBP1.
  • Researchers in this study developed a method to identify short introns using RNA-Seq data, finding hundreds of conserved short introns across different human cell types that are often alternatively spliced.
  • The study reveals that splicing efficiency for these short introns can be enhanced by their secondary structures, and their removal can change the reading frame of mRNAs, indicating that current gene prediction models may not effectively account for these introns in the human transcriptome.
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Gordonia phages Bowser and Schwabeltier are newly isolated phages infecting Gordonia terrae 3612. Bowser and Schwabeltier have similar siphoviral morphologies and their genomes are related to each other, but not to other phages. Their lysis cassettes are atypically situated among virion tail genes, and Bowser encodes two tyrosine integrases.

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Statistics are the primary tools for assessing relationships and evaluating study questions. Unfortunately, these tools are often misused, either inadvertently because of ignorance or lack of planning, or conspicuously to achieve a specified result. Data abuses include the incorrect application of statistical tests, lack of transparency and disclosure about decisions that are made, incomplete or incorrect multivariate model building, or exclusion of outliers.

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A proposed tangential flow ultrafiltration method was compared to the widely used ultracentrifugation method for efficiency and efficacy in concentrating, size selecting, and minimizing the aggregation state of a silver nanoparticle (AgNP) colloid while probing the AgNPs' SERS-based sensing capabilities. The ultrafiltration method proved to be more efficient and more effective and was found to tremendously boost the SERS-based sensing capabilities of these AgNPs through the increased number of homogeneous SERS hot spots available for a biotarget molecule within a minimal focal volume. Future research studies and applications addressing the physiochemical properties or biological impact of AgNPs would greatly benefit from ultrafiltration for its ability to generate monodisperse colloidal nanoparticles, to eliminate excess toxic chemicals from nanoparticle synthesis, and to obtain minimum levels of aggregation during nanoparticle concentration.

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