Crevicular fluid levels of interleukin-1alpha and interleukin-1beta during experimental gingivitis in young and old adults.

The purpose of the present investigation was to study the effect of age on interleukin-1alpha (Il-1alpha) and interleukin-1beta (Il-1beta) production during experimental gingivitis. One group of five young subjects (20-22 years old) and another group of five older subjects aged 61-65 years were involved in the study. A professional plaque control programme was undertaken to establish healthy gingival conditions at baseline.