Relationship between plasma aldosterone and left ventricular structure and function in patients with essential hypertension.

Recent experimental studies demonstrated that elevation of plasma aldosterone is associated with an increased collagen accumulation resulting in myocardial fibrosis. The aim of this study was to evaluate the association of circulating aldosterone with cardiac structural and functional changes in patients with essential hypertension. The authors examined 39 patients (aged 51 +/- 14 years, 13 male, 26 female) with essential hypertension.

[The renin-angiotensin-aldosterone system and serum lipoproteins in patients with essential hypertension].

The authors investigated the relationship between the activity of the renin-angiotensin-aldosterone system and serum lipid levels in patients with essential hypertension (EH). They examined 72 patients with EH stage I and II WHO classification (group A, n = 72, age bracket 16-70 years). They investigated the plasma renin activity (PRA), plasma aldosterone (PA) and total cholesterol (TCH), HDL, LDL cholesterol and triglycerides (TG).