Publications by authors named "Zaborowska L"

Article Synopsis
  • - Smooth Muscle Tumor of Uncertain Malignant Potential (STUMP) is a rare tumor that doesn't fit the typical definitions of benign (leiomyoma) or malignant (leiomyosarcoma), and its symptoms can mimic benign conditions without specific markers for diagnosis.
  • - A case study of a 42-year-old woman illustrates the diagnosis and treatment of STUMP; she initially underwent surgery for what was thought to be a benign leiomyoma, and post-surgery, histopathology revealed it was actually a STUMP, yet she is recurrence-free after 9 months.
  • - Managing STUMP requires a tailored strategy that involves various medical fields, taking into account the patient's future fertility plans, as well as addressing the
View Article and Find Full Text PDF

Background: Oncology research is increasingly adopting new clinical trial models that implement the concept of precision medicine. One of these is the basket clinical trial design. Basket clinical trials allow new treatments to be evaluated across multiple tumor types.

View Article and Find Full Text PDF

Polycystic ovary syndrome (PCOS) is a common gynaecological/endocrine disorder that affects 5%-10% of women of reproductive age. Its association with psychiatric conditions is well known. This study aimed to evaluate personality, temperamental, and stress-related characteristics among PCOS patients by comparing them with a control group.

View Article and Find Full Text PDF

Objectives: Human papillomavirus infection is one of the most common sexually transmitted infections. Long-term exposure to the HPV leads to high-grade squamous intraepithelial lesions affecting cervical cancer. Knowledge about the distribution of HPV genotypes is crucial to guide the introduction of prophylactic vaccines.

View Article and Find Full Text PDF

Objectives: Human papillomavirus infection is one of the most common sexually transmitted infections. Histological LSIL in 70-80% of cases will regress spontaneously, while a subset is associated with residual risk for a future precancerous lesion. This study evaluates the performance of HPV genotypes for LSIL preceded by normal or mildly abnormal Pap smear.

View Article and Find Full Text PDF

Objectives: Human papillomavirus (HPV) infection is one of the most common sexually transmitted diseases. Long-term exposure to the HPV is a known cause of squamous intraepithelial lesions that consequently lead to cervical cancer development. The loop electrosurgical excision procedure (LEEP) conization is an established early cervical cancer treatment method.

View Article and Find Full Text PDF

Background: For research with human participants to be ethical, risk must be in a favorable balance with potential benefits. Little is known about the risk/benefit ratio for pediatric cancer phase II trials testing targeted therapies.

Objective: Our aim was to conduct a systematic review of preliminary efficacy and safety profiles of phase II targeted therapy clinical trials in pediatric oncology.

View Article and Find Full Text PDF

Objectives: To establish the rates of publication and reporting of results for interventional clinical trials across Polish academic medical centres (AMCs) completed between 2009 and 2013. We aim also to compare the publication and reporting success between adult and paediatric trials.

Design: Cross-sectional study.

View Article and Find Full Text PDF