Diltiazem cold cardioplegia in coronary artery surgery: effects on myocardial function and ischemia.

This study was undertaken to evaluate the myocardial preservation obtained by adding a calcium channel blocker, diltiazem (200 mcg/kg of body weight) to cold potassium cardioplegia in 24 patients with coronary artery disease who underwent myocardial revascularization, and were randomly divided into a treated Group D and a Control Group C. No significant differences were noted between the groups in cardiac electrical arrest and recovery time, recovery rhythm, mechanical function recovery, inotropic support, stroke index, or cardiac index. After cardiopulmonary bypass, the stroke index decreased by 13.

[Prevention of myalgias caused by succinylcholine with a small dose of a non-depolarizing muscle relaxant].

Precurarisation with 1 mg/15 kg d-tubocurarine was given before 1.5 mg/kg succinylcholine to obtain muscle relaxation for tracheal intubation in 100 patients, whereas 1 mg/kg succinylcholine only was administered to 100 controls. Serious postoperative myalgia fell from 8% to 0%, and forms of average intensity from 21% to 8% in the curarised group.

[Changes in 2,3-diphosphoglycerate in polytransfused patients during neurosurgery].

2,3-DPG values following administration of fructose 1,6-diphosphate were followed neurosurgery in 28 polytransfused patients. Intraerythrocyte 2,3-DPG values were already significantly over the baseline 8 hr after administration of the organic phosphate.

[Intravenous ethyl alcohol in metabolic resuscitation].

Intravenously administered ethyl alcohol may be effective as analgesic and hypotensive peripheric vasoactive drug. In the Intensive Care Departments parenteral ethanol administration is infrequent because no "sure dosage" can be suggested in adults and children. Liver, kidney and C.

[Althesin in anesthesia for neuroradiologic arteriographic studies].

Following mention of problems of cerebral haemodynamics and the action of various anaesthetics on endocranial pressure, a personal anaesthesiological technique based on the use of althesin in drip form is reported and its advantages listed.

[Anesthesia problems of the multiply-injured patient].

Anaesthesia in the case of subjects with multiple injuries is commonly a short-term emergency measure, in which a certain time is available for the implementation of intensive antishock therapy, or else anaesthesia for deferred emergency situations. Since the introduction of ketamine and althesin, the anaesthesiological risk has greatly reduced. Althesin has the best therapeutic index of all anaesthetics and the least myocardial toxicity.