Tandospirone prevents anesthetic-induced respiratory depression through 5-HT receptor activation in rats.

Respiratory depression is a side effect of anesthetics. Treatment with specific antagonists or respiratory stimulants can reverse respiratory depression caused by anesthetics; however, they also interfere with the sedative effects of anesthetics. Previous studies have suggested that tandospirone may ameliorate respiratory depression without affecting the sedative effects of anesthetics.

Enhancing the sustainability of rubber materials: Dual benefits of wet mixing technology and recycled rubber's honeycomb reinforcement structure.

The world's three leading tire manufacturers have proposed specific timelines for using recycled materials. For instance, Michelin targets an increase in the proportion of sustainable materials in tires to 40 % by 2030 and aims to produce 100 % of its tires from bio-based, renewable, or recyclable materials as of 2050. In such a context, this study introduced wet mixing technology to apply recycled rubber (RR) in highly wear-resistant tire tread compounds.

Dietary Effects of Probiotic Bacteria, AV5 on Growth, Serum and Mucus Immune Response, Metabolomics, and Lipid Metabolism in Nile Tilapia ().

In the present study, we investigated the effect of dietary supplementation with the probiotic AV5 (OR647358) on the growth, serum and mucus immune responses, metabolomics, and lipid metabolism of . Fishes (27.2 ± 1.

Analysis of the dust cleaning performance of a branch-type nozzle.

To solve the problem of uneven dust cleaning in filter cartridges, a simple and easy-to-install "branch-type" nozzle structure was designed to improve cleaning efficiency. In this study, numerical simulations, range analysis methods, orthogonal experimental design, back-blowing experiments, and powder cleaning experiments were conducted. By choosing the back-blowing uniformity as the evaluation index for cleaning performance, with the flow distribution coefficient , length of branch pipe , and outlet diameter of main pipe as the factors, and ignoring the interaction between factors, an orthogonal experiment was designed to simulate the fluid flow field of nine different nozzle structures installed in the back-blowing model.