Publications by authors named "Z Yılmaz"
The enzyme phosphatidylinositide-3-kinase (PI3K) regulates cellular proliferation and apoptosis. Somatic mutations in the PIK3CA gene can accelerate these processes and significantly contribute to the development and progression of breast cancer. This study aimed to ascertain the PIK3CA gene mutations in breast cancer patients and investigate their correlation with certain clinicopathological characteristics.
View Article and Find Full Text PDFObjective: Eating disorders (EDs) are serious psychiatric disorders with an estimated 3.3 million healthy life-years lost worldwide yearly. Understanding the course of illness, diagnostic transitions and remission, and their associated genetic correlates could inform both ED etiology and treatment.
View Article and Find Full Text PDFBackground And Aim: Kidney transplant recipients frequently experience a wide range of metabolic complications, including weight changes, which significantly impact patient outcomes and graft function, yet the relationship between weight gain and transplant outcomes remains poorly understood. This systematic review and meta-analysis aimed to synthesise existing evidence on the influence of weight gain on patient and graft outcomes following kidney transplantation to enhance clinical practice and optimise post-transplant care strategies.
Materials And Methods: A literature search was conducted across databases such as PubMed and Scopus for peer-reviewed studies published up to 8 August 2024.
Article Synopsis
- The study investigated adverse neonatal outcomes in children born to mothers with different eating disorders, including anorexia nervosa (AN), bulimia nervosa (BN), and eating disorder not otherwise specified (EDNOS).
- It analyzed data from over 1.5 million births in Denmark from 1991 to 2015, comparing outcomes based on whether the eating disorder diagnosis was recent (within 2 years of conception) or past (over 2 years before conception).
- Findings showed that recent eating disorders, especially AN, were linked to higher risks of low birthweight, small-for-gestational-age, and preterm birth, emphasizing the need for better prevention and monitoring of eating disorders during pregnancy.
Article Synopsis
- Canine distemper virus (CDV) leads to serious health issues in dogs, particularly affecting the central nervous system, but little is known about how certain biomarkers relate to the disease.
- The study aimed to compare serum biomarkers between 10 dogs infected with CDV and 10 healthy dogs and to analyze correlations between serum and cerebrospinal fluid (CSF) biomarkers.
- Results showed that certain inflammatory cytokines and antioxidant levels were significantly higher in dogs with CDV, and specific cytokines in CSF were correlated with those in serum, suggesting these could assist in diagnosing neurological involvement in CDV infections.