Publications by authors named "Z Win"
Background/objectives: The diagnosis of encephalitis is a challenging problem due to the heterogeneity of clinical presentations. The objective was to determine the etiology, clinical features, laboratory parameters, radiological findings, and in-hospital outcome of acute encephalitis syndrome (AES) cases in Myanmar.
Methods: A prospective descriptive study was conducted at the Neuromedical Ward of Yangon General Hospital from March to August 2023.
Background: Cardiovascular diseases (CVD) remains a leading cause of mortality in Myanmar. Despite the burden, CVD preventive services receive low government and donor budgets, which has led to poor CVD outcomes.
Methods: We conducted a cost-effective analysis and a budget impact analysis on CVD prevention strategies recommended by the WHO.
Alzheimer's disease heterogeneity revealed by neuroanatomical normative modeling.
Alzheimers Dement (Amst)
March 2024
Introduction: Overlooking the heterogeneity in Alzheimer's disease (AD) may lead to diagnostic delays and failures. Neuroanatomical normative modeling captures individual brain variation and may inform our understanding of individual differences in AD-related atrophy.
Methods: We applied neuroanatomical normative modeling to magnetic resonance imaging from a real-world clinical cohort with confirmed AD ( = 86).
Article Synopsis
- The rise of angiosperm-dominated tropical rainforests occurred shortly after the Cretaceous-Paleogene transition, prompting examination of rare Paleocene fossil wood to understand anatomical changes.
- Researchers analyzed 11 Paleocene fossil wood specimens from Myanmar, describing their anatomical features and identifying affinities with present-day plant families, including a new species and genus called Compitoxylon paleocenicum.
- The findings indicate long-lasting plant groups in South Asia, showcasing both modern and primitive wood features, suggesting early diversity and stability of tropical flora during the angiosperm evolution.
During preclinical evaluations of drug candidates, several physicochemical (p-chem) properties are measured and employed as metrics to estimate drug efficacy in vivo. Two such p-chem properties are the octanol-water partition coefficient, Log , and distribution coefficient, Log , which are useful in estimating the distribution of drugs within the body. Log and Log are traditionally measured using the shake-flask method and high-performance liquid chromatography.
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