Publications by authors named "Z Wiener-Megnazi"

Introduction: Repeated implantation failure is a common challenge in daily practice. Homocysteine and vitamin B12 have been associated with reproductive processes among patients undergoing in vitro fertilization; however, their involvement in repeated implantation failure has not been assessed. We explored possible associations of serum homocysteine and vitamin B12 with repeated implantation failure.

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Article Synopsis
  • The study compares the effectiveness of Intra Cytoplasmic Sperm Injection (ICSI) with conventional in vitro fertilization (IVF) using donor sperm in women.
  • Results showed no significant differences in fertilization, cleavage, pregnancy, or live birth rates between ICSI and conventional IVF, but ICSI led to a lower proportion of high-quality embryos.
  • The findings suggest that ICSI does not improve outcomes related to age-related oocyte quality and may not be the preferred method for insemination in these cases.
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Background: Endometrial injury is an intentional damage made to the endometrium, usually produced by a Pipelle catheter. Over the last two decades, endometrial injury has been studied to improve implantation rates and decrease the incidence of implantation failure in invitro fertilization (IVF) cycles. Recently, additional studies of endometrial injury, performed not only in patients with implantation failure but also in intrauterine insemination cycles, have been conducted, and the endometrial injury made by hysteroscopy has been researched.

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We report a live birth from a heavily fragmented embryo which continued cleavage to a fully expanded blastocyst. A 32-year-old patient underwent 2 IVF cycles without achieving pregnancy. In the first cycle, 2 embryos with fragmentation were transferred; in the second, all embryos were fragmented and no embryo transfer was performed.

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Purpose: The present study evaluated the association between oxidative parameters in embryo cryopreservation medium and laboratory and clinical outcomes.

Methods: This prospective laboratory study was conducted in an IVF unit in a university-affiliated hospital with 91 IVF patients undergoing a frozen-thawed embryo transfer cycle. Following thawing, 50 μL of embryo cryopreservation medium was retrieved from each cryotube and tested by the thermochemiluminescence (TCL) assay.

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