Publications by authors named "Z W Quan"
We aimed to explore the role of circular RNA 0043256 (circ_0043256) in gastric cancer (GC) and its underlying mechanisms. The impact of circ_0043256 silencing on the proliferation, migration, apoptosis, and aerobic glycolysis of MKN-45 and AGS cells induced by CoCl2 was assessed through the utilization of CCK-8, wound healing assay, flow cytometry, and metabolic analysis. The interaction between circ_0043256 and miR-593-5p, as well as the involvement of the miR-593-5p/RRM2 axis in gastric cancer, were confirmed via luciferase assay, Western blot, and bioinformatics analysis.
View Article and Find Full Text PDFIn this study, the effects of ultrasound-assisted enzymatic hydrolysis on the production of antioxidant and antiosteoporotic peptides derived from oysters were investigated. Results showed that ultrasound-assisted enzymatic hydrolysis significantly enhanced the peptide content, free radical scavenging ability, and ferric reducing antioxidant power of total oyster protein hydrolysate (TOPH), with optimal results achieved at 200 W (TOPH-200). Correspondingly, ultrasound treatment at 200 W increased the exposure of hydrophobic regions, reduced α-helix content, and facilitated the generation of small molecular weight peptides in TOPH.
View Article and Find Full Text PDFArticle Synopsis
- Spinal cord injury (SCI) is a major neurological disorder causing serious motor, sensory, and autonomic issues, primarily due to poor axon regeneration and remyelination.
- Recent research highlights new therapeutic strategies that target key molecules and pathways to enhance myelin repair in SCI, using both lab and animal studies.
- The review emphasizes the challenges in applying these findings to clinical settings, focusing on safety and delivery methods, while positing targeted remyelination therapies as a hopeful treatment approach for SCI.
Unmanned probes, mainly powered by solar panels, are effective tools for exploiting space resources to expand the human habitat. However, it remains a great challenge for the unmanned probes to actively repel multiscale dust particles in space. Inspired by the synergistic antifouling mechanism of fly wings and legs, a biomimetic dynamic antifouling surface (BDAS) was prepared based on a combination of self-assembly and template inversion.
View Article and Find Full Text PDFBackground: As a commonly identified cancer in clinics, pancreatic cancer (PC) has poor prognostic outcomes. This work focused on clarifying the association between MIR-766-3P expression and PC development and progression, as well as the possible role as a biomarker in PC.
Methods: MIR-766-3P expression within the human PC cells and samples was measured through miRNA RT-PCR.