Immunohistochemical analysis of CD9, CD29 and epithelial to mesenchymal transition in triple-negative breast cancer.

Background: Triple-negative breast carcinomas (TNBC) are a heterogeneous group of tumors with mostly aggressive behaviour and poor prognosis. In association with their aggressive behavior and chemoresistance to treatment, the concept of epithelial-mesenchymal transition (EMT) has come to the fore. CD9 and CD29 proteins are associated with EMT and may play a role in TNBC progression.

Effect of HCl on a sorption of mercury from flue gas evolved during incineration of hospital waste using entrained flow adsorbers.

Small incinerators of dangerous wastes, including those from hospitals, are a source of emissions of highly variable compositions and concentrations. Mercury is a very dangerous pollutant causing neurotoxicity in human organism. The effect of HCl concentration on adsorption of mercury on activated carbon-based sorbent was studied for the incineration of hospital waste in a 250 kg/h capacity unit.

Meckel's Diverticulum in Children-Parameters Predicting the Presence of Gastric Heterotopia.

Background: The presence of gastric ectopic mucosa in Meckel's diverticulum is associated with a higher risk of development of complications. The aim of the present study was to investigate which demographic/clinical parameters predict the presence of gastric heterotopia in Meckel's diverticulum.

Methods: This was a retrospective cohort study conducted in a single institution (University Hospital Ostrava, Czech republic).

Correlation of lipoprotein(a) with the extent of coronary artery disease in patients with established coronary atherosclerosis: gender differences.

Objective: To assess the gender differences in correlation lipoprotein(a) concentration with the extent of coronary artery disease in patients with established coronary artery disease.

Patients And Methods: Blood lipids and lipoprotein(a) concentrations were measured in 351 consecutive patients (256 men and 95 women) who underwent coronary angiography between January and May 2010, and who had established coronary atherosclerosis (angiography score >1). A modified angiographic Gensini Score was used.

DEAD-box RNA helicase is dispensable for mitochondrial translation in Trypanosoma brucei.

DEAD-box RNA helicase, a putative subunit of the mitochondrial ribosome of Trypanosoma brucei, has been down-regulated in the procyclic and bloodstream stage by RNA interference. Although ablation of the transcript leads to a week growth phenotype in the procyclic cells, the protein does not seem to be essential for mitochondrial translation under standard cultivation conditions, as shown by an assay that allows visualization of the de novo synthesized proteins. Furthermore, we show that synthesis of cytochrome c oxidase subunit I and cytochrome b does not occur in the mitochondrion of the bloodstream stage.