[Exrercise tolerance in patients with coronary artery disease after coronary artery stenting].

The aim of the research is to investigate the impact of coronary stenting on exercise tolerance after 4-8 week and after 12-15 months. The study involved total 90 patients with coronary artery disease, who underwent coronary stenting. All patients underwent clinical examination, including an assessment of their condition, the frequency of angina attacks, echocardioscopy, resting ECG was recorded in all the patients in the standard 12 -lead veloergometry.

[Genetic aspects of atrial fibrillation in coronary artery disease patients].

To examine the relationship I/D polymorphism of the angiotensin-converting enzyme (ACE) gene and polymorphism A1166S of angiotensin II type 1 receptor (AT2R1) gene with the development of atrial fibrillation (AF) in patients with coronary artery disease (CAD), the residents of Kharkiv region. The study involved 318 patients with CAD, of whom 54 (17,0%) patients with CHD and AF were included in group I, 264 (93,0%) patients without AF - in group II. The control group included 35 people without atherosclerotic and morphological changes of spacecraft.

[Comparison of the therapeutic effect of the Warfarin and Rivaroksaban among the patients with not-valuate fibrillation of atrium].

In this article the results of comparative assessment of the efficiency of the Rivaroksaban and Varfarine for prevention of stroke and systemic embolic complications in middle and high- stroke risk patients with nonvalvular artial fibrillation are presented. Detailed analysis of some risk factors is conducted according to scales: CHADS2, CHA2DS2-VASc and HAS-BLED. The frequency of development of endpoints is defined (stroke, TIA, system embolism, cardiac infarction or death due to cardiovascular reasons, or combination of outcomes) according to initial risk and anticoagulant treatment.