[Iodide metabolism in the rat thyroid at early and remote periods following the long-term exposure of external fractionated gamma-radiation].

The research was made into the effects of 20-fold exposure to external gamma-radiation (0.1-0.5 Gy) on the activities of the key steps of iodide metabolism (absorption, oxidation and organification) in the rat thyroid as well as on its morphologic structure at the early (1 day) and remote (30 and 180 days) periods after the radiation.

[Effects of chronic administration of high doses of potassium iodide on iodine metabolism in the rat thyroid gland].

The effect of various doses of KI on iodine methabolism in rat thyroid gland was investigated. Treatment with 1, 3, 10, 100 and 500 physiological daily doses of KI for 14 days had no influence on blood level of thyroid hormones. However, increased administration of KI was accompanied by the increase of iodine in the thyroid gland tissue by 60-121% due to 35-108% and 94-128% increases of protein-bound and free fractions respectively.

[The effect of one-time external low- and high-dose gamma-irradiation on rat thyroid structure at the acute and remote periods].

A study of the morphological structure of the thyroid was made at the acute (1, 3, 6 hours) and remote periods (1, 4, 24, 48 weeks) following the external gamma-irradiation at doses of 0.25-5.0 Gy using histologic and electron microscopic methods.

[Functional and morphological characterization of rat thyroid gland at remote periods following single high and low dose radiation exposure].

A study of the morphological structure and functional activity of the rat thyroid gland was carried out after 22 months following a single exposure to external radiation. The 3-month-old animals were irradiated with doses of 0.25, 0.

[Effect of long-term exposure to low dose gamma-irradiation on the rat thyroid status].

The effect of long-term exposure to low-dose external radiation on the rat thyroid status was studied. The experiments were carried out on Wistar female rats. The single doses absorbed were 0.