Optimization of stereotactic body radiotherapy treatment planning using a multicriteria optimization algorithm.

Purpose: To provide high-quality and efficient dosimetric planning for various types of stereotactic body radiotherapy (SBRT) for tumor treatment using a multicriteria optimization (MCO) technique fine-tuned with direct machine parameter optimization (DMPO).

Methods And Materials: Eighteen patients with lung (n=11), liver (n=5) or adrenal cell cancer (n=2) were treated using SBRT in our clinic between December 2014 and June 2015. Plans were generated using the RayStation™ Treatment Planning System (TPS) with the VMAT technique.

Whole brain radiotherapy with a conformational external beam radiation boost for lung cancer patients with 1-3 brain metastasis: a multi institutional study.

Background: To determine the outcome of patients with brain metastasis (BM) from lung cancer treated with an external beam radiotherapy boost (RTB) after whole brain radiotherapy (WBRT).

Methods: A total of 53 BM patients with lung cancer were treated sequentially with WBRT and RTB between 1996 and 2008 according to our institutional protocol. Mean age was 58.

[Prevention of post-transfusion cytomegalovirus infection: recommendations for clinical practice].

Based on a review of the literature, guidelines for the clinical use of cytomegalovirus (CMV) seronegative cellular blood products are presented. The clinical fields of application include obstetrics and foetal, neonatal, and transplantation medicine. Seronegative blood products are indicated for the transfusion of pregnant women, foetuses, and neonates until the 3rd month of life.