Effect of photodynamic therapy with two photosensitizers on the microtensile bond strength of a universal adhesive to affected dentin.

Background: This study aimed to evaluate the impact of photodynamic therapy (PDT) using two photosensitizers, methylene blue and indocyanine green, on the microtensile bond strength of a universal adhesive to caries-affected dentin.

Methods: The occlusal enamel of 60 third molars was cut to expose the inner one-third of the dentin. Artificial caries were induced through a pH cycling process.

Comparison of Dentin Caries Remineralization with Four Bioactive Cements.

The treatment of deep carious lesions involves the use of ion-releasing agents to seal the lesions. These agents release minerals, leading to the remineralization of the remaining demineralized dentin. This study aimed to compare the dentin caries remineralization with bioactive cements.

Evaluation of Wear Properties of Four Bulk-Fill Composites: Attrition, Erosion, and Abrasion.

Purpose: Wear and increased surface roughness are among the reasons for failure of posterior composite restorations. Considering the widespread use of bulk-fill composites in the posterior region, information about their wear resistance is imperative. The aim of this study was to compare the wear and surface roughness of four bulk-fill composite resins with a conventional composite.

Cytotoxicity and Antibacterial Activity of Toothpastes and Mouthwashes Available in the Iranian Market.

Toothpastes and mouthwashes contain chemicals that may be harmful to oral tissues. This study assessed the cytotoxicity and antibacterial activity of toothpastes and compare the Iranian and foreign toothpastes and mouthwashes available in the Iranian market in this respect. Twenty samples (13 toothpastes and 4 mouthwashes) were selected.

Silymarin and neurodegenerative diseases: Therapeutic potential and basic molecular mechanisms.

Background: Neurodegenerative diseases (NDDs) are primarily characterized by selective neuronal loss in the brain. Alzheimer's disease as the most common NDDs and the most prevalent cause of dementia is characterized by Amyloid-beta deposition, which leads to cognitive and memory impairment. Parkinson's disease is a progressive neurodegenerative disease characterized by the dramatic death of dopaminergic neuronal cells, especially in the SNc and caused alpha-synuclein accumulation in the neurons.