Publications by authors named "Z Sen"

Background: Affective modulation of startle reflex (AMSR) is a widely used experimental tool for assessing emotional reactivity. Previous research has shown inconsistent findings of emotional reactivity in amplitude in bipolar patients (BP). This study examined emotional reactivity (ER) in euthymic BP compared to healthy controls using both subjective and objective measures.

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Rationale: Ketamine, a non-competitive NMDA receptor antagonist, produces antidepressant effects at subanesthetic doses. The therapeutic effect, however, is often accompanied by cognitive side effects, including memory impairments. Yet, the specific effects of ketamine on different processes of implicit and explicit memory remain to be elucidated.

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  • The study investigates the effectiveness of two methods—plate screw system and intramedullary nailing—used in treating humeral shaft fractures, specifically looking at stress shielding through finite element analysis.
  • Advanced imaging techniques, specifically CT scans, were utilized to create a detailed 3D model of the humerus, which was then analyzed using specialized software.
  • Results indicated that intramedullary nailing produced less stress and fewer concentrations on the implants compared to the plate system, suggesting it may be a more effective method for osteosynthesis in these fractures.
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Background: Neuroimaging studies have provided valuable insights into the macroscale impacts of antidepressants on brain functions in patients with major depressive disorder. However, the findings of individual studies are inconsistent. Here, we aimed to provide a quantitative synthesis of the literature to identify convergence of the reported findings at both regional and network levels and to examine their associations with neurotransmitter systems.

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  • - Enteroviruses (EV) are the leading cause of aseptic meningitis in children, and their detection in cerebrospinal fluid (CSF) using PCR can help confirm diagnoses and guide treatment.
  • - A study of patients aged 1 month to 17 years revealed that 38.2% had PCR-confirmed EV meningitis, with pleocytosis present in 70.5% of these cases, while convulsions were notably more common in PCR-positive patients without pleocytosis.
  • - The research suggests that accurate diagnosis of EV meningitis through PCR can reduce unnecessary hospital stays and antibiotic usage, ultimately minimizing complications related to care.
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