Publications by authors named "Z Sekhniashvili"

1.034 inhabitants (270 men, 459 women and 305 children) were examined in Racha region (North-western Georgia) on endemic goiter at the age from 1 to 75. The investigated population was selected by randomized method.

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Altogether 24 patients with diffuse toxic goiter were examined after surgical intervention and thiamazole therapy. In addition to clinical methods the levels of T- and B-lymphocytes, immunoregulatory cells (T-helpers and T-suppressors) and immunoglobulins of different classes were determined before and after therapy. A method of spontaneous and complementary rosette formation and monoclonal antibodies (Ortho) were used for the determination of the content of T- and B-lymphocytes.

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Female patients with the menopausal syndrome (MS) manifestations showed a steeper increment of diastolic arterial blood pressure (ABP) and heart rate, as compared to normal subjects, in both phases of the menopause, irrespective of whether cardialgia was present or not; moreover, half of the patients showed negative electrocardiographic dynamics. Hemodynamic shifts in response to bicycle ergometry were similar in both menopausal phases and showed steeper increments in ABP and heart rate, as compared to those of normal subjects. Excessive ABP rise in response to exercise is mostly associated with cardialgias.

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