Publications by authors named "Z Salama"

Article Synopsis
  • Leniolisib (JOENJA) is an oral drug developed by Pharming Group NV to treat immunodeficiency disorders, specifically targeting a protein called PI3Kδ.
  • It received its first approval in March 2023 for treating activated PI3Kδ syndrome (APDS) in patients aged 12 and older and is currently under review in the EU for the same condition.
  • Development for treating Sjögren's syndrome has been stopped; this article outlines the key milestones leading to leniolisib's approval for APDS.
View Article and Find Full Text PDF

The problem of shortage in freshwater resources in many countries around the world has led to the use of unconventional water resources such as treated wastewater and agricultural drains water to bridge the gap between the demand and supply. However, the open nature of most agricultural drains and the spread of population cumulation around them has made them vulnerable to many organic and inorganic pollutants. One of the artificial methods used to enhance the self-purification process in polluted streams is submerged biofilters (SB).

View Article and Find Full Text PDF

Background And Aim: Rabies is considered a highly fatal zoonotic disease and many deaths in humans have been associated with dog bites. This study was designed to prepare an oral anti-rabies vaccine in the form of baits to eliminate the disease in free-roaming dogs and subsequently protect humans from dog bites.

Materials And Methods: The Evelyn Rokintniki Abelseth (ERA) rabies virus strain was propagated in baby hamster kidney cell cultures and adjusted to the recommended dose for application.

View Article and Find Full Text PDF

Water scarcity is one of the most serious problems facing many countries. In addition, water pollution could lose more water. A submerged biofilter (SB) is used to enhance the self-purification process in polluted streams.

View Article and Find Full Text PDF