Publications by authors named "Z S Reich"

Article Synopsis
  • Mimivirus bradfordmassiliense is a giant virus that infects Acanthamoeba species, leading to significant changes in the host's gene expression during infection.
  • Long- and short-read sequencing techniques revealed a complex transcriptome of the host, showing a total of 22,604 transcripts and major downregulation in genes involved in crucial cellular functions like cytoskeleton stability and DNA synthesis, indicating cell cycle arrest.
  • The virus itself exhibited dynamic gene expression trends, with early stages focusing on DNA-related processes and later stages emphasizing lipid metabolism and protease activity, suggesting extensive disruption of the host's cellular organization.
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The balance between linear electron transport (LET) and cyclic electron transport (CET) plays an essential role in plant adaptation and protection against photo-induced damage. This balance is largely maintained by phosphorylation-driven alterations in the PSII-LHCII assembly and thylakoid membrane stacking. During the dark-to-light transition, plants shift this balance from CET, which prevails to prevent overreduction of the electron transport chain and consequent photo-induced damage, towards LET, which enables efficient CO assimilation and biomass production.

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Cellular lineage tracking provides a means to observe population makeup at the clonal level, allowing exploration of heterogeneity, evolutionary and developmental processes and individual clones' relative fitness. It has thus contributed significantly to understanding microbial evolution, organ differentiation and cancer heterogeneity, among others. Its use, however, is limited because existing methods are highly specific, expensive, labour-intensive, and, critically, do not allow the repetition of experiments.

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