Synergistic antibacterial and wound healing effects of chitosan nanofibers with ZnO nanoparticles and dual antibiotics.

One concern that has been considered potentially fatal is bacterial infection. In addition to the development of biocompatible antibacterial dressings, the screening and combination of new antibiotics effective against antibiotic resistance are crucial. In this study, designing hemostasis electrospun composite nanofibers containing chitosan (CS), polyvinyl pyrrolidone (PVP) and Gelatin (G) as the major components of hydrogel and natural nanofibrillated sodium alginate (SA)/polyvinyl alcohol (PVA) and ZnO nanoparticles (ZnONPs) combination as the nanofiller ingredient, has been investigated which demonstrated significant potential for accelerating wound healing.

Vaccination with OprB porin, and its epitopes offers protection against A. baumannii infections in mice.

A. baumannii is a deadly antimicrobial resistance pathogen that acquires drug resistance through different mechanisms. Therefore, it is necessary to investigate all its virulence factors and design effective vaccines against it.

Nano hydrogel with bacterial nanocellulose and bitter almond oil nanoemulsions for enhanced wound healing: In-vivo and in-vitro characterization.

Biocompatibility, good mechanical properties, infection prevention, and anti-inflammatory are the requirements of an ideal wound dressing for the care and treatment of skin wounds. In this study, the nanohydrogels as wound dressing, were fabricated by bacterial nanocellulose (BNC), polyvinyl alcohol (PVA), and gellan gum. Bitter almond oil nanoemulsion (BAO-NE) was made with ultrasonic force and incorporated into the nanohydrogels in concentrations of 2, 4, and 6 %.

Antibiotic delivery in the presence of green AgNPs using multifunctional bilayer carrageenan nanofiber/sodium alginate nanohydrogel for rapid control of wound infections.

This study constructed bilayer nano-hydrogels using solvent casting and electrospinning techniques. The first layer consisted of a hydrogel containing sodium alginate and gellan gum, while the second layer was a carrageenan/polyvinyl alcohol nanofibrous membrane. The nanohydrogels were prepared with different doses of doxycycline antibiotic (0.