Spontaneous gas bubbling in microporous oxygenators.

During operation of the microporous membrane oxygenators at some conditions, gas microbubbles penetrate into the blood. This effect, so-called spontaneous bubbling, takes place even when the blood pressure is higher than the gas pressure. This phenomenon was confirmed experimentally both in a model cell with hydrophobic microporous hollow fibers being used in the oxygenators and in in vitro tests on the actual microporous hollow fiber oxygenator.

[Low-flow membrane oxygenation of blood in patients with diffuse purulent peritonitis].

Small-flow membranous oxygenation of the blood was used in 45 patients with peritonitis in the multiple organ failure phase. In ten cases blood oxygenation was combined with hemofiltration. MOCT 19-03 (Kvant Research and Production Unit) and Gambro FH hemofilters (Sweden) were employed.

[Effects of heterogeneity of gas channels on carbon dioxide output of membrane oxygenators].

A relationship between the carbon dioxide output of the oxygenators and the value of ventilating gas flow is analyzed. It is shown that a potential inhomogeneity of gas channels may result from the lower efficiency of the oxygenators. The tests of the MOST oxygenators have indicated that the achieved homogeneity of their gas chambers is sufficient for carbon dioxide to be effectively removed.

[Slow-flow membrane oxygenation of blood as a method of detoxication in the treatment of patients with abdominal sepsis].

The criteria of efficacy of small-flow membranous oxygenation of the blood were defined and the duration of this measure optimized in the treatment of 30 patients hospitalized at the department for abdominal surgery, Moscow District Research and Clinical Institute, after operations for abdominal diseases and purulent complications thereof performed at hospitals of the Moscow district. Small-flow membranous oxygenation of the blood brought about a trend to normalization of the peripheral blood parameters which were changed as a result of inflammation; it was conducive to normalization of the blood acid-base status and oxygen extraction by tissues, and had an immunostimulating effect in general. The level of medium-weight molecular peptides may be regarded as a criterion of the efficacy of small-flow membranous oxygenation of the blood.