Development, Validation, and Application of the LC-MS/MS Method for Determination of 4-Acetamidobenzoic Acid in Pharmacokinetic Pilot Studies in Pigs.

Each drug has pharmacokinetics that must be defined for the substance to be used in humans and animals. Currently, one of the basic analytical tools for pharmacokinetics studies is high-performance liquid chromatography coupled with mass spectrometry. For this analytical method to be fully reliable, it must be properly validated.

The Prevalence of and in Small Wild Rodents in Poland.

Rodents are a large group of mammals that can be carriers of zoonotic pathogens such as strains that cause yersiniosis. The prevalence of and was determined in 214 small wild rodents from south-eastern Poland. Samples were analyzed by precultivation and PCR.

The prevalence of Yersinia enterocolitica in game animals in Poland.

Natural reservoirs of Yersinia (Y.) enterocolitica comprise different animal species, but little is known about the role of wild animals in the epidemiology of yersiniosis. The aim of the study was to evaluate the prevalence of Y.

Monitoring of Yersinia enterocolitica strains from free-living animals using different methods.

The aim of the study was to monitor Y. enterocolitica strains from free-living animals captured during 2011-2014 hunting seasons in Poland using warm (ITC) and cold (PSB) enrichment and molecular examination. Over 1600 samples have been cultured.

The influence of experimental Yersinia enterocolitica infection on the pregnancy course in sows--preliminary studies. III. Histopathological lesions.

The aim of the study was to evaluate the anatomo- and histopathological lesions in internal organs of sows and their stillborn piglets after experimental Y. enterocolitica infection in different phases of pregnancy. Twelve pregnant sows were divided into 4 groups, infected per os on 33 (n = 3), 54 (n = 3) and 89 (n = 3) day of pregnancy with the pathogenic Y.