Publications by authors named "Z Pekkolay"
Article Synopsis
- The study aimed to compare various clinical and hormonal characteristics, treatment methods, and survival outcomes of ectopic Cushing's syndrome (ECS) between male and female patients.
- Data was collected from 11 medical centers, evaluating 54 patients (28 females and 26 males), and found similarities in age, clinical presentation, and hormone levels despite some differences like higher rates of diabetes and osteoporosis in males.
- Overall, the results showed comparable disease progression, treatment responses, and remission rates between sexes, but indicated that males experience more severe conditions such as hyperglycemia and osteoporosis.
Objective: Primary hypophysitis might be challenging to diagnose, and there is a lack of evidence regarding optimal treatment strategies due to rarity of the disease. We aim to investigate the clinical features and compare the outcomes of different management strategies of primary hypophysitis in a large group of patients recruited on a nationwide basis.
Design: A retrospective observational study.
Article Synopsis
- - This study aimed to identify factors affecting disease-free survival (DFS) in patients with medullary thyroid carcinoma (MTC), as previous research in this area has been limited.
- - Researchers analyzed data from 257 patients, finding that 51% had persistent/recurrent disease while 49% had no evidence of disease at follow-up, with various factors like age, metastasis, and initial response influencing DFS outcomes.
- - The key finding was that the lack of an excellent response after initial treatment is the strongest predictor of worse DFS, highlighting the need for diligent follow-up even in patients who initially respond well.
COMPARISON OF C-PEPTIDE LEVELS IN MONOGENIC FORMS OF DIABETES WITH OTHER TYPES OF DIABETES: A SINGLE-CENTER STUDY.
Acta Endocrinol (Buchar)
February 2024
Objective: This study aimed to evaluate the utility of C-peptide levels in the differentiation of monogenic forms of diabetes from type 1 diabetes mellitus (T1DM) and type 2 diabetes mellitus (T2DM) in clinical practice.
Subjects And Methods: A total of 104 patients aged >16 who visited the Dicle University's Faculty of Medicine between April 2011 and December 2020 and were diagnosed with monogenic diabetes by genetic analysis or with T1DM and T2DM were randomly selected for retrospective evaluation. The C-peptide levels of these patients at the time of diagnosis of diabetes were compared.