Transplantable Murine Tumors in the Studies of Peptide Antitumor Vaccines.

Numerous studies have shown that antitumor vaccines based on synthetic peptides are safe and can induce both CD8 and CD4 tumor-specific T cell responses. However, clinical results are still scarce, and such approach to antitumor treatment has not gained a wide implication, yet. Recently, particular advances have been achieved due to tumor sequencing and the search for immunogenic neoantigens caused by mutations.

[About the term «newborn» in forensic medicine].

The aim of this work is to prove necessity of using the term «newborn» as common both in forensic medicine and general medicine (from the moment of birth till 28th day), to show legality of using the term «signs of recent birth», to demonstrate the importance of understanding not only the higher border in definition of neonatal period but its initial moment that is necessary to solve some investigative questions and determine legal capacity of people and provide criminal justice defense of citizens' life and health.

[Postmortem computed tomography of the frozen corpse].

The purpose of the work is to identify the possibilities of computed tomography in establishing postmortem changes in the bones of the skeleton and internal organs during in a frozen corpse. The article describes a case from thanatological practice with the performance of a pre-sectional computed tomography of a corpse of a young woman found in a forest in a state of complete freezing. As a result of the study, CT images of frozen internal organs were obtained, which are never found in clinical practice.

Dependence of Quantum Dot Toxicity In Vitro on Their Size, Chemical Composition, and Surface Charge.

Semiconductor nanocrystals known as quantum dots (QDs) are of great interest for researchers and have potential use in various applications in biomedicine, such as in vitro diagnostics, molecular tracking, in vivo imaging, and drug delivery. Systematic analysis of potential hazardous effects of QDs is necessary to ensure their safe use. In this study, we obtained water-soluble core/shell QDs differing in size, surface charge, and chemical composition of the core.

[Ophthalmotonus examination in children (4-17 years) to determine the time of death].

This article presents data on the analysis of intravital and postmortem intraocular pressure (IOP) values in children aged 4 to 17 years. Intravital ophthalmotonus values were analyzed according to medical records of 991 children; the mean value for the age of 4-17 years was determined as 19±3 mm Hg with a confidence level of more than 95%. Postmortem IOP values were studied in 158 deceased subjects (28.