[The blood kinin system in patients with inflammatory and functional diseases of the colon].

The condition of the kinin system was studied in 89 patients with inflammatory and functional diseases of the colon. The relatedness has been revealed of the intestine microflora changes and of the blood kinin system activity to morphological changes in the colon mucosa.

[Approaches to combined therapy of pulmonary tuberculosis in adolescents excreting drug-resistant Mycobacterium tuberculosis].

The data are presented on 138 adolescents with active, advanced tuberculosis. M. tuberculosis were detected in the sputum and bronchial lavage of 75(54.

[Carbohydrate metabolism impairment and specific features of the course of tuberculosis in adolescents with diabetes mellitus].

The paper deals with the detection of carbohydrate metabolic disturbances in adolescents with tuberculosis and analyzes their impact on the course of a specific process. Borderline carbohydrate metabolic disorders were identified in 10.8% of the 130 patients examined.

[Relationship of tuberculosis course in adolescents with acute phase blood proteins and genetic types of haptoglobin].

The phenotype of haptoglobin (Hp) was determined and Hp and alpha 1-antitrypsin (alpha 1-AT) were many times measured in the sera of 131 adolescents with first identified tuberculosis. The phenotype of Hp was found to produce no effects on tuberculosis morbidity among adolescents, but Hp2-2 carriers fall ill more frequently if they have a baseline gastrointestinal abnormality. In tuberculosis patients with Hp2-2, resolution of infiltrative changes in the lung tissue occurs less rapidly than in those with other Hp variants.

[The detection of mycobacteria in children and adolescents by using the polymerase chain reaction].

A polymerase chain reaction (PCR) was used for determination of mycobacterial DNA in clinical samples from children and adolescents. The results were positive in 23 and 53% of cases, respectively, while standard microbiological methods failed to show presence of any bacteria in the samples. Case histories contained information on high incidence of positive Mantoux test.