Publications by authors named "Z Ozgen"
Article Synopsis
- The study examined how low dose cyclosporin A (CsA) can protect rat kidneys from damage caused by ischemia-reperfusion (IR) injury, focusing on mechanisms of cell death.
- Three groups were tested: a control group, an IR group (exposed to restricted blood flow), and an IR + CsA group (received CsA before the IR procedure).
- Results showed that CsA significantly improved kidney function and reduced injury markers compared to the IR group, indicating its protective effects against IR-related kidney damage.
Article Synopsis
- * Monitoring neuromuscular function (NMM) in children is essential to ensure proper muscle relaxation during surgery and to support fast recovery post-anesthesia.
- * The article reviews different NMM methods, discussing their pros and cons, and emphasizes the need for a standardized approach in pediatric anesthesia practice.
Article Synopsis
- * This study investigated the use of dental follicle mesenchymal stem cells (DF-MSCs) from healthy donors on patients with Pemphigus vulgaris (PV), showing that DF-MSCs can significantly lower T-cell proliferation and inflammatory cytokine levels while boosting regulatory T cells.
- * The results indicate DF-MSCs may help restore immune balance in PV patients, but more clinical trials are needed to validate their potential as a treatment option.
Objectives: To identify the unmet needs of breast cancer patients undergoing radiotherapy METHODS: A pretest-posttest single-group experimental design, a variation of the experimental research approach, was employed in this investigation. The study's sample consisted of 28 breast cancer patients undergoing radiotherapy at the radiation oncology clinic of a training and research hospital between November 2021 and April 2022. The sample size was determined using G*Power 3.
View Article and Find Full Text PDFPurpose: To investigate development of radiation pneumonitis (RP) in relation to pulmonary function, dosimetric factors, and transforming growth factor beta-1 (TGFβ1) expression in irradiated breast cancer patients.
Methods: A total of 49 breast cancer patients who received post-operative radiotherapy (RT) were evaluated in terms of pulmonary function tests (PFTs), quality of life (QoL), development of RP, dosimetric factors, cytokine levels, and lung high-resolution computed tomography (HRCT) before and after RT. ROC analysis was performed for performance of dosimetric factors in predicting RP, while frequencies of single nucleotide polymorphisms (SNPs) genotyped for TGFβ1 (rs11466345 and rs1800470) were also evaluated.