Publications by authors named "Z Mohsenifar"
Background And Objective: Hepatocellular carcinoma (HCC) is recognized as one of the major public health problems and deadly malignancies worldwide. Today, the use of compounds of natural origin in the treatment of cancer and other diseases has been of interest to researchers. Marine compounds such as algae have anti-cancer effects.
View Article and Find Full Text PDFIntroduction And Importance: Gastrointestinal bleeding is a serious health threat, especially when it originates from the small intestine, often termed small bowel bleeding (SBB). Hemangioendothelioma, a rare vascular tumor, can be a significant yet uncommon cause of gastrointestinal bleeding. This case report highlights hemangioendothelioma's diagnostic challenges and clinical significance in SBB.
View Article and Find Full Text PDFObjective: Hepatocellular carcinoma (HCC) is a significant type of liver cancer. In spite of many treatment approaches, its treatment is still associated with challenges. Therefore, new approaches with minimal side effects are necessary for its treatment.
View Article and Find Full Text PDFArticle Synopsis
- Immune stressors like LPS disrupt gut microbiota, leading to gut dysbiosis, which can interfere with mammary gland development during puberty and potentially increase breast cancer risk later in life.
- The study tests the hypothesis that prebiotics, specifically Lentinula edodes Cultured Extract (AHCC), can counteract the negative effects of LPS by examining cytokine levels, microRNA expressions, and tumor development in mice following LPS exposure.
- Results indicate that while LPS leads to long-term changes in cytokine and microRNA levels in mammary glands, AHCC helps regulate these changes, particularly by counteracting harmful microRNAs associated with tumor progression, suggesting possible dietary interventions
Article Synopsis
- Gastric cancer is a complicated disease with various molecular subtypes that affect treatment and prognosis, with high mortality and limited therapies available.
- Microsatellite instability (MSI) is identified as a favorable subgroup in gastric cancer, particularly noted for its good prognosis, but there is little data regarding its prevalence in the Middle East, especially Iran.
- A study analyzing 53 Iranian gastric cancer samples revealed that about 7.5% exhibited high MSI, primarily among older patients, females, and those with specific tumor characteristics, such as larger size and distal location.