Publications by authors named "Z Mladenovic"
Background: Left atrial stiffness index (LASI), defined as the ratio of early diastolic transmitral flow velocity/lateral mitral annulus myocardial velocity (E/e') to peak atrial strain, reflects reduced left atrial (LA) compliance and represents an emerging marker that can be used for noninvasive measurement of fibrosis of LA in patients with mitral regurgitation (MR).
Objective: To investigate the impact of chronic MR in children and adolescents on the remodeling and function of the LA, quantified through strain parameters and diastolic function.
Methods: The study included fifty patients (n= 50) diagnosed with primary and secondary chronic MR lasting at least 5 years.
Article Synopsis
- Prenatal cardiology focuses on early detection and treatment of congenital heart defects (CHD) through fetal echocardiography and interventions, aiding both pediatric and adult patients.
- The study emphasizes the importance of left atrial strain (LAS) in evaluating fetal heart conditions and predicting potential structural and functional disorders during specific gestational periods.
- The findings suggest that LAS measurements can provide valuable insights for clinical decision-making, enhancing care for both cardiac and noncardiac complications in pregnancy.
Background: Left atrial (LA) strain analysis has emerged as a noninvasive technique for assessing LA function and early detection of myocardial deformation. Recently, its application has also shown promise in the pediatric population, spanning diverse cardiac conditions that demand accurate and sensitive diagnostic measures.
Objective: This research article endeavors to explore the role of LA strain parameters and contribute to the growing body of knowledge in pediatric cardiology, paving the way for more effective and tailored approaches to patient care.
Introduction: Sodium-glucose cotransporter-2 (SGLT2) inhibitors are integral in treating patients with heart failure, regardless of the existence of diabetes mellitus. In light of their benefits on the heart muscle, the question of their effect on acute coronary syndrome is raised, and a hypothesis as to whether they can be implemented in its treatment is proposed. The aim of the article was to indicate the potential of using SGLT2 inhibitors in the treatment of myocardial infarction (MI).
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- Sodium-glucose cotransporter 2 (SGLT2) inhibitors play a vital role in treating heart failure by promoting glucose excretion and reducing reabsorption.
- A systematic review examined 12 randomized controlled trials involving a total of 83,878 patients, focusing on various SGLT2 inhibitors like canagliflozin, dapagliflozin, and empagliflozin.
- Findings indicate SGLT2 inhibitors significantly lower the odds of heart failure hospitalization and related cardiovascular issues, highlighting their effectiveness in improving heart failure outcomes.