The Need to Set up a Biobank Dedicated to Lymphoid Malignancies: Experience of a Single Center (Laboratory of Clinical and Experimental Pathology, University Côte d'Azur, Nice, France).

Several therapies to improve the management of lymphoma are currently being investigated, necessitating the development of new biomarkers. However, this requires high-quality and clinically annotated biological material. Therefore, we established a lymphoma biobank including all available biological material (tissue specimens and matched biological resources) along with associated clinical data for lymphoma patients diagnosed, according to the WHO classification, between 2005 and 2022 in the Laboratory of Clinical and Experimental Pathology, Nice, France.

Exploring Antioxidant Activity, Organic Acid, and Phenolic Composition in Strawberry Tree Fruits ( L.) Growing in Morocco.

This study aimed to explore the main biochemical components and the antioxidant capacity of five strawberry tree fruits using three antioxidant essays within the ecotypic comparison scheme, to find out the most valuable fruit presenting disease-preventing properties. Total phenols, total flavonoids, total anthocyanins, antioxidant activity (DPPH, ABTS, and β-Carotene bleaching assays), pH, titratable acidity, soluble solids, and moisture content were investigated in five strawberry tree genotypes belonging to several areas in Morocco. Phenolic compounds were also identified using high performance chromatography (HPLC), with a diode array detector (DAD).

Establishment of a Collection of Blood-Derived Products from COVID-19 Patients for Translational Research: Experience of the LPCE Biobank (Nice, France).

In only a few months after its inception, the COVID-19 pandemic lead to the death of hundreds of thousands of patients and to the infection of millions of people on most continents, mostly in the United States and in Europe. During this crisis, it was demonstrated that a better understanding of the pathogenicity, virulence, and contagiousness of SARS-CoV-2, all of which were initially underestimated, was urgently needed. The development of diagnostic tests to identify SARS-CoV-2 or to detect anti-SARS-CoV2 antibodies in blood, of vaccines, and of preventive and curative treatments has been relying on intense activity of scientists in academia and industry.

Multidimensional analysis of genetic background and environmental factors: Cases of atopy in asthmatic children.

The present work aimed, through a multidimensional analysis of a data set related to 76 asthmatic children (2-16 years), to their family, and to their antecedents, to establish typical profiles of children with asthma, combining similar or even identical characteristics. A questionnaire was presented to the parents concerning possible consanguinity, prematurity of the child, birth order, skin prick test results, presence of animals, indoor dampness, medical history, and cases of atopy among the children and their antecedents. The links between variables were first identified by means of chi-square tests.