[Activity of metabolic enzymes of saliva with neuroendocrine tumors of the lung of various degrees of malignancy.].

Up to the present time, problems of optimizing the methods of diagnosis and predicting the course of lung cancer, which occupies the leading positions in the structure of oncological diseases, remain topical. The purpose of the study was to study the characteristics of the activity of metabolic salivary enzymes in neuroendocrine tumors of the lung, depending on the degree of malignancy. In the casecontrol study, 156 people took part, divided into 2 groups: primary (neuroendocrine lung tumors, n=56) and control (conventionally healthy, n=100).

[The system of lipid peroxidation and antioxidant protection of saliva in lung cancer.].

The aim of the study was to study the parameters of the lipid peroxidation system and antioxidant protection in saliva in lung cancer of various histological types. In the case-control study, 740 volunteers participated in the study, which were divided into 3 groups: primary (lung cancer, n = 347), comparison group (non-malignant pulmonary pathologies, n = 178) and control (conditionally healthy, n = 215). Questioning, biochemical examination of saliva, histological verification of the diagnosis were conducted to all participants.

[Study of arginase activity of mixed saliva in cancer].

The aim of the study was to investigate the activity of arginase of mixed saliva with the subsequent application of the results obtained in clinical laboratory diagnostics. Arginine metabolic parameters were studied in particular arginase activ- ity, concentration of nitric oxide, urea and uric acid. There was found a three-fold increase of arginase activity and a four- fold reduction of nitric oxide in mixed saliva of patients on the background of cancer.

[STATISTICAL FEATURES OF BREAST CANCER INCIDENCE IN THE OMSK REGION].

Statistical patterns of breast cancer were studied in the Omsk Region in order to optimize early diagnosis and improve the effectiveness of treatment. It was found that the proportion of breast cancer patients in stage I in all age groups was 22. 9%, which was identical with that in the majority of regions of Russia (15 26%) and was close to the average population indices (18.

[Status Indicators of Lipid Peroxidation and Endogenous Intoxication in Lung Cancer Patients].

Background: Problems of optimization diagnosis methods and prognosis for lung cancer remain unsolved. Lung cancer occupied the leading positions among cancer diseases.

Aims: Establishing change patterns in the parameters of endogenous intoxication and lipid peroxidation in the saliva of patients with lung cancer depending on the histologic type of tumor.