[Impaired maternal and fetal hemodynamics in the pathogenesis of gestosis].

The study was undertaken to examine the specific features of maternal and fetal hemodynamics in the pathogenesis of gestosis and to develop differential approaches to obstetric policy. For this, a total of 345 pregnant women at risk for gestosis were examined. This condition was prevented using aspirin and trental in 60 women.

[Pathogenesis of systemic hemodynamic disorders and choice of optimal obstetrical strategy in pregnant patients with gestosis].

A total of 810 pregnant women were examined in order to elucidate the pathogenesis of hemodynamic disorders in gestosis. The main group consisted of 460 patients with gestosis of different severity and the control group included 150 women with uneventful pregnancy. Central and regional hemodynamics in normal pregnancy were studied in detail by modern diagnostic methods (echocardiography and dopplerometry) and the relationship between the detected shifts and the function of the utero-placento-fetal circulation was shown.

[Central and regional hemodynamics during the physiological course of pregnancy and the systemic circulatory disorders in gestoses].

Ninety-one patients with physiological pregnancy and gestosis were studied. This included examinations of maternal central hemodynamics and Doppler study of blood flow in the system of carotids, renal artery and its branches, uterine and umbilical arteries. The volumetric maternal central hemodynamic parameters were found to increase concurrently with a reduction in peripheral vascular resistance during physiological pregnancy, which is associated with the emergence and development of a fetoplacental complex.

[The clinico-diagnostic importance of evaluating the blood flow in the mother-placenta-fetus system in EPH gestosis].

A dynamic dopplerometry of the blood flow in the mother-placenta-fetus system, carried out in 79 women with EPH gestosis, revealed a direct correlation between uteroplacental and fetoplacental blood flow disturbances and gestosis, hypertension, edematous syndrome, and proteinuria severity. Comprehensive assessment of the blood flow in both uterine arteries and umbilical artery are preferable. When third-degree circulatory disturbances are revealed in the mother-placenta-fetus system, cesarean section is recommended.