Epidemiology of Rectal Cancer Patients in the Kingdom of Bahrain: A Retrospective Cohort Study.

Aim And Background: As rectal cancer diagnosis becomes more prevalent due to the increased awareness caused by campaigns, this study aims to focus on the demographics of patients diagnosed with rectal cancer in the Kingdom of Bahrain.

Methods: A retrospective cross-sectional study design was conducted on 184 patients diagnosed with primary or second primary rectal cancer. Stage and site of tumor at diagnosis, gender, BMI, family history, histology, and metastasis are discussed throughout the paper.

Effects of Combination Taping Technique on Disability, Functional Capacity, and Knee Isokinetic Torque in Patients with Knee Osteoarthritis: A Blinded Randomized Controlled Study.

Background: Treatments that combine both elastic and rigid taping in knee osteoarthritis have not yet been investigated in the literature. Thus, the purpose of the present study is to investigate how the combination taping technique affects functional status, disability, and quadricep isokinetic torque in cases of knee osteoarthritis. Patient Methods: A total of fifty-four patients were assigned to the experimental group or control group.

Fullerenol nanoparticles and AMF application for optimization of Brassica napus L. resilience to lead toxicity through physio-biochemical and antioxidative modulations.

Crop plants are severely affected by heavy metals (HMs), leading to food scarcity and economical loss. Lead (Pb) is outsourced by use of lead-based fertilizers, batteries, mining, smelting and metal processing. It significantly reduces growth, development and yield of crops cultivated on contaminated sites.

The contraceptive active ingredient levonorgestrel disrupts the physiology of Macrocyclops albidus.

Active pharmaceutical ingredients, such as levonorgestrel (LNG), continue to increase in aquatic ecosystems and are detected in environmental matrices; however, their ability to bioaccumulate and cause reproductive, developmental, and biochemical defects in benthic organisms, such as Macrocyclops albidus, is unknown. This study investigated the effects of LNG on the oxidative stress response, reproduction, and development of M. albidus.

New α-glucosidase inhibitors and antioxidants in optimized Jack leaves extract identified by gC-MS-based metabolomics and molecular docking.

Our earlier research demonstrated α-glucosidase inhibitory (AGI) and antioxidant activities of the optimised extract of leaves. It was reported having numerous compounds, although it was unclear which compounds exhibit the bioactivities as well as their binding interaction to the enzyme. This study aimed to identify the compounds possessing AGI and antioxidant activities in the extract utilising GC-MS-based metabolomics, and to analyse the ligand-enzyme binding interactions molecular docking.