Orchestrated response from heterogenous fibroblast subsets contributes to repair from surgery-induced stress after airway reconstruction.

Surgery of the tracheobronchial tree carries high morbidity, with over half of the complications occurring at the anastomosis. Although fibroblasts are crucial in airway wound healing, the underlying cellular and molecular mechanisms in airway reconstruction remain unknown. We hypothesized that airway reconstruction initiates a surgery-induced stress (SIS) response, altering fibroblast communication within airway tissues.

The emerging role of S100A4 and S100A14 proteins in colorectal cancer progression.

Colorectal cancer (CRC) is the third most frequent type of cancer and the second leading cause of cancer-related deaths globally. Despite a thorough understanding of its biology, etiology, and epidemiology, an estimated 1.8 million new cases are diagnosed each year, and 900000 people die as a result of malignancy.

A case of treating polypoidal choroidal vasculopathy subretinal fluid by subthreshold micropulse laser.

Purpose: Assess the effectiveness of a subthreshold micropulse laser for treating a patient with polypoidal choroidal vasculopathy and subretinal fluid.

Observations: A 55-year-old female presented with left eye blurring vision and metamorphopsia, and her visual acuity was 20/60. Optical coherence tomography (OCT) and OCT angiography showed subretinal fluid and pigmented epithelium detachment with a small polyp under the retinal pigmented epithelium, which was diagnosed as polypoidal choroidal vasculopathy.

Effect of ophthalmic preparation of methyldopa on induced ocular hypertension in rabbits.

Glaucoma is a type of ocular disorder with multifaceted etiologies characterized by progressive optic nerve damage and ultimately loss of visual field. This study aimed to evaluate the possible intraocular pressure (IOP) lowering effect of an ophthalmic preparation of methyldopa (MD) in corticosteroid-induced ocular hypertension in rabbits. Forty New Zealand white male rabbits were assigned to the experiment and then randomly divided into five groups (n = 8).

Abscesses in different body sites among children: a single-center prospective study.

Objectives: An abscess is a localized collection of pus contained within a fibrous capsule. In this study, we aimed to determine the demographic pattern, common anatomical sites, risk factors, and the microbial profile of abscesses in different body sites among children.

Methods: We conducted a prospective study in our pediatric surgical department among children with abscesses in different body sites between January 2019 and December 2022.