Adapted Counseling Care Model for Management of Female Sexual Dysfunction Among Women Living With and Without HIV.

Background And Objective: Sexual health research among women living with human immunodeficiency virus (HIV) has focused mainly on sexual practices and risk behaviors, with little consideration for treating sexual dysfunction and improving sexual satisfaction. The aim of this pilot study was to assess the effectiveness of an adaptive counseling care model in the management of female sexual dysfunction (FSD) among women living with HIV and without HIV in northern Nigeria.

Methods: This was a prospective cohort study of 200 women with HIV and a matched comparison arm of 200 women without HIV.

Multimorbidity clusters and their associations with health-related quality of life in two UK cohorts.

Background: Identifying clusters of multiple long-term conditions (MLTCs), also known as multimorbidity, and their associated burden may facilitate the development of effective and cost-effective targeted healthcare strategies. This study aimed to identify clusters of MLTCs and their associations with long-term health-related quality of life (HRQoL) in two UK population-based cohorts.

Methods: Age-stratified clusters of MLTCs were identified at baseline in UK Biobank (n = 502,363, 54.

Complexes of vertebrate TMC1/2 and CIB2/3 proteins form hair-cell mechanotransduction cation channels.

Calcium and integrin-binding protein 2 (CIB2) and CIB3 bind to transmembrane channel-like 1 (TMC1) and TMC2, the pore-forming subunits of the inner-ear mechano-electrical transduction (MET) apparatus. These interactions have been proposed to be functionally relevant across mechanosensory organs and vertebrate species. Here, we show that both CIB2 and CIB3 can form heteromeric complexes with TMC1 and TMC2 and are integral for MET function in mouse cochlea and vestibular end organs as well as in zebrafish inner ear and lateral line.

Green-synthesized silver nanoparticle-enhanced nanofiltration mixed matrix membranes for high-performance water purification.

This study presents the fabrication and characterization of mixed matrix membranes (MMMs) incorporating green-synthesized silver nanoparticles (AgNPs) using Hibiscus Rosa sinensis extract within a polyethersulfone (PES) matrix for nanofiltration (NF) application. The membranes were evaluated for their pure water permeability, salt rejection, dye removal, and antifouling performance. Results showed that the membrane with 0.

Fabrication of novel pullulan/carboxymethyl chitosan-based edible film incorporated with ultrasonically equipped aqueous zein/turmeric essential oil nanoemulsion for effective preservation of mango fruits.

This study aimed to develop ultrasonically-assisted, alcohol-free, and noncorrosive aqueous zein/turmeric essential oil (TEO)-loaded nanoemulsions (NEs) to stimulate pullulan/carboxymethyl chitosan (P/CMCS)-based edible films for mango fruit preservation. The influence of innovative sonicated zein/TEO-based NEs (ZTNEs) as nanofillers on the physico-mechanical characteristics of the resulting P/CMCS edible films was investigated. A stable and well-dispersed ZTNE was achieved using 20 % zein with 10 min of ultrasound treatment, leading to a reduced droplet size (194.