Aspergillosis of the nose and paranasal sinuses in neutropenic patients at an oncology center.

Invasive aspergillosis of the nose and paranasal sinuses is one of the presentations of aspergillosis in granulocytopenic patients with neoplastic disorders. It is most prevalent among patients with leukemia and granulocytopenia and is associated with a high mortality rate. We report five cases of invasive aspergillosis of the nose and paranasal sinuses in profoundly neutropenic patients treated with broad spectrum antibiotics.

In vitro antibiotic activity of 11 beta-lactam antibiotics in a cancer center.

Two-thousand, five-hundred and twenty-four bacterial isolates were tested against 11 new beta-lactam antibiotics in a prospective study conducted in a cancer center. E. coli, P.

Evaluation of a Cordia-IC enzyme-linked immunosorbent assay kit for the detection of circulating immune complexes.

A commercial kit (Cordia-IC) from Cordis Laboratory, Miami, Fla., was compared with the Raji cell radioimmunoassay for its ability to detect circulating immune complexes (CIC) in sera from 30 control subjects and 118 patients with infectious diseases. The 118 patients were categorized into the following groups: (i) 23 patients with bacterial endocarditis, (ii) 41 patients with bacteremia from an infected intravascular catheter or access device, and (iii) 54 patients with Staphylococcus aureus bacteremia related to a deep tissue infection.

Hickman-Broviac catheter use in cancer patients.

Seventy-nine patients who had Hickman-Broviac (H-B) catheters inserted over a 1-year period were studied. There were 52 patients in the hematological group and 27 patients in the solid tumor group. Complications associated with the H-B catheters were infection and venous thrombosis, with infection being more common.