Publications by authors named "Z Lakhani"
The details of how macrophages control different healing trajectories (regeneration vs. scar formation) remain poorly defined. Spiny mice (Acomys spp.
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- - The KONAR-MFO is a versatile medical device first used in humans in 2013 that offers flexibility and improved delivery, making it suitable for both pediatric and adult patients with complex heart defects.
- - This study reviews three rare cases treated with the KONAR-MFO for conditions like ALCAPA, post-myocardial infarction VSR, and PVL after mitral valve replacement, all of which showed excellent outcomes within a year.
- - Follow-ups indicated complete closure of lesions without major complications, highlighting successful transcatheter management for patients deemed high-risk for surgery.
Introduction: Transcatheter pulmonary valve implantation has been an effective treatment for dysfuntional right ventricular tract outflow tract (RVOT). Defining a landing zone before the intervention is crucial in patients with native RVOT. Improper sizing and undefined landing zone will lead to embolization.
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- Pannexin 1 (PANX1) is a glycoprotein found in various tissues, including skin, and forms channels that let ions and small molecules like ATP pass through.
- The study reveals that PANX1 is frequently expressed in human melanoma tumors and reducing its levels or blocking its function leads to decreased cell growth and increased melanin production in melanoma cell lines.
- PANX1 appears to influence tumor growth and progression by affecting signaling pathways, particularly the Wnt/β-catenin pathway, highlighting its potential as a target for melanoma treatment.
Background: The purpose of this study was to determine whether currently published outcome measures of physical function would be suitable for use for older adults with a hip fracture. The measures that were considered were the Musculoskeletal Function Assessment (MFA) Instrument, the Older Americans' Resources and Services (OARS) Multidimensional Functional Assessment Questionnaire physical function subscale, the Toronto Extremity Salvage Score (TESS), and the Short Form-36 (SF-36). Following suggestions by an expert panel and patient interviews, the MFA was not tested further.
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