[Interphase chromatin in lymphocytes in sex differentiation disorders].

Interphase chromatin of peripheral lymphocytes was studied in patients aged 6 to 20 years with Turner and Morris's syndromes by AO labeled fluorometry using the authors' modification of DNP cell thermal denaturation. It was shown that the lymphocyte chromatin melting profiles represent the curves with seven maxima at the following temperatures: 47 degrees, 55 degrees, 65 (+/- 2)degrees, 78 (+/- 1)degrees, 82, 88 (+/- 1)degrees, 92 (+/- 2)degrees C (P less than 0.01).

[Use of Soviet-made menotropin for the treatment of hypogonadotropic hypogonadism in women].

Investigation of the therapeutic efficacy of menopause gonadotropin (MPG), made in the USSR, in patients with hypogonadotropic hypogonadism demonstrated MPG to possess the FSH-activity. In a number of patients with hypogonadotropic hypogonadism MPG treatment led to the occurrence of the ovular menstrual cycle, confirmed both clinically and by hormonal studies. But sometimes MPG proved to be ineffective, this pointing to the necessity of individual choice of a drug dose and the number of therapeutic courses.