Publications by authors named "Z Kuloglu"

Article Synopsis
  • Effective surveillance methods for seasonal respiratory viruses are crucial for managing outbreaks, and this study evaluated the effectiveness of air screening in a tertiary hospital and campus over five months.
  • The study found that the overall viral positivity was significantly higher on campus (55.0%) compared to the hospital (38.0%), with Influenza A being the most prevalent pathogen at both sites.
  • The research identified distinct peaks in Influenza A and RSV-A cases, with air screening showing potential as an early warning system for respiratory infections, except for rhinoviruses.
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The monogenic causes of very-early-onset inflammatory bowel disease (VEO-IBD) have been defined by genetic studies, which were usually related to primary immunodeficiencies. Receptor-interacting serine/threonine-protein kinase-1 (RIPK1) protein is an important signalling molecule in inflammation and cell death pathways. Its deficiency may lead to various clinical features linked to immunodeficiency and/or inflammation, including IBD.

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In this study, we aimed to investigate the changes in the B cell subpopulations after homologous or heterologous COVID-19 boosters. Blood samples were collected after baseline (3-5 months after two doses of CoronaVac), 1 and 3 months after BNT162b2 (n=28 and n=6), and CoronaVac (n=7 and n=4) boosters. Peripheral blood mononuclear cells (PBMCs) were isolated and stained with B cell markers, the ratios of naïve (CD19+CD20+CD27-), memory (CD19+CD20+CD27+), memory B cells expressing IgG (CD19+CD20+CD27+IgG+), and effector memory B cells (CD19+CD20+CD27+CD38+) were identified with flow cytometry.

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