*K-means and cluster models for cancer signatures.

We present *K-means clustering algorithm and source code by expanding statistical clustering methods applied in https://ssrn.com/abstract=2802753 to quantitative finance. *K-means is statistically deterministic without specifying initial centers, etc.

Mutation Clusters from Cancer Exome.

We apply our statistically deterministic machine learning/clustering algorithm *K-means (recently developed in https://ssrn.com/abstract=2908286) to 10,656 published exome samples for 32 cancer types. A majority of cancer types exhibit a mutation clustering structure.

Importance of correlations of gross motoric functions data and functional independence for management of children with motoric disabilities.

The aim of the rehabilitation therapy is to improve the level of functional independence and decrease degree of disability. The optimization of programs of rehabilitation means functional improvement of the person, and this approach is a basis of effective management. To evaluate the correlation of Gross Motoric Function Data and Functional Independence Measure for children with cerebral palsy.

[Comparative analysis of prognostic value of epileptic encephalopathies and symptomatic epilepsy in children with cerebral palsy].

Cerebral dysfunction due to epilepsy is not currently well-understood and needs to be further investigated. We have observed patients with static encephalopathy (cerebral palsy) of nearly equal severity with epileptic encephalopathy and symptomatic epilepsy and have had carried out comparative analysis of prognosis among these groups. The work is based on the results of investigation of 121 patients admitted to the Center of child neurology and neurorehabilitation during the period 2000-2005.

Prognostic value of gross motor function measure to evaluate the severity of cerebral palsy.

Early adequate evaluation of motor development and prognosis of degree of long-term motor disability is very important not only for parents, but also for correct management of goal oriented rehabilitation treatment and for planning of preventive measures. To estimate the value of Gross Motor Function Measure in evaluation of severity of cerebral palsy, for prognostic counseling with parents and for planning of clinical management. Total of 397 children aged 1 to 12 years at study onset with cerebral palsy were observed for up to 3,5 years during the period from 2002 to 2005.