Publications by authors named "Z J Isherwood"

We introduce HumanBrainAtlas, an initiative to construct a highly detailed, open-access atlas of the living human brain that combines high-resolution in vivo MR imaging and detailed segmentations previously possible only in histological preparations. Here, we present and evaluate the first step of this initiative: a comprehensive dataset of two healthy male volunteers reconstructed to a 0.25 mm isotropic resolution for T1w, T2w, and DWI contrasts.

View Article and Find Full Text PDF

Color percepts of anomalous trichromats are often more similar to normal trichromats than predicted from their receptor spectral sensitivities, suggesting that post-receptoral mechanisms can compensate for chromatic losses. The basis for these adjustments and the extent to which they could discount the deficiency are poorly understood. We modeled the patterns of compensation that might result from increasing the gains in post-receptoral neurons to offset their weakened inputs.

View Article and Find Full Text PDF

Natural scenes contain several statistical regularities despite their superficially diverse appearances (e.g., mountains, rainforests, deserts).

View Article and Find Full Text PDF

Inherited color vision deficiencies typically result from a loss or alteration of the visual photopigments absorbing light and thus impact the very first step of seeing. There is growing interest in how subsequent steps in the visual pathway might be calibrated to compensate for the altered receptor signals, with the possibility that color coding and color percepts might be less severely impacted than the receptor differences predict. These compensatory adjustments provide important insights into general questions about sensory plasticity and the sensory and cognitive processes underlying how we experience color.

View Article and Find Full Text PDF

The 1/f amplitude spectrum is a statistical property of natural scenes characterising a specific distribution of spatial and temporal frequencies and their associated luminance intensities. This property has been studied extensively in the spatial domain whereby sensitivity and visual preference overlap and peak for slopes within the natural range (α ≈ 1), but remains relatively less studied in the temporal domain. Here, we used a 4AFC task to measure sensitivity and a 2AFC task to measure visual preference and across a wide range of spatial (α = 0.

View Article and Find Full Text PDF