'One of the greatest injustices of our time': The impact of social representations of modern slavery in the UK-A mixed methods approach.

This study aimed to examine how social representations of modern slavery and immigration become entangled in newspaper media. 2672 UK newspaper articles were collated from 2013 to 2022 and analysed using Content Analysis (Descendant Hierarchical Classification) and Critical Discourse Analysis (CDA). Two themes and corresponding extracts were identified from the content analysis output and analysed using CDA allowing for the exploration of the role of the hegemonic social representations to understanding how discourses of modern slavery are reproduced through the othering in relation to ethnicity and migration.

Lessons Learned From Clinical Studies in Centronuclear Myopathies: The Patient Perspective-A Qualitative Study.

Background: Since 2014, several clinical studies focusing on centronuclear myopathies have been conducted, including a prospective natural history study, a gene transfer clinical trial and a clinical trial using an antisense oligonucleotide. Dedicated patient organizations have played an important role in this process. The experience of members of these organizations, either as a study participant, parent or as a patient organization member communicating with the sponsors are potentially very informative for future trial design.

Changes in Age Distribution and Maternal Mortality in a Subset of the U.S., 2014-2021.

Introduction: This study aimed to determine the association between changes in age distribution and maternal mortality rates (MMR) in a subset of the United States between 2014 and 2021.

Methods: A serial cross-sectional analysis of birthing individuals aged 15-44 years from 2014 to 2021 was performed. States that had not adopted the pregnancy checkbox as of 2014 were excluded from the primary analysis.

The experience of clinical study and trial participation in rare diseases: A scoping review of centronuclear myopathy and other neuromuscular disorders.

The design of a clinical trial for a rare disease can be challenging. An optimal study design is required to effectively study the clinical outcomes for possible therapies for these types of disorders. Understanding the study participants' experiences as well as barriers and facilitators of participation are important to optimize future research and to inform clinical trial management.