Management of chest tube after thoracoscopic lung resection in children with congenital lung malformation: a multicenter retrospective study.

This study aimed to investigate the safety and effect of omitting chest tubes after thoracoscopic lobectomy in children with congenital lung malformation. A multicenter retrospective study was performed with 632 thoracoscopic lobectomy CLM patients in four hospitals between 2014.1 and 2023.

An fMRI study on the generalization of motor learning after brain actuated supernumerary robot training.

Generalization is central to motor learning. However, few studies are on the learning generalization of BCI-actuated supernumerary robotic finger (BCI-SRF) for human-machine interaction training, and no studies have explored its longitudinal neuroplasticity mechanisms. Here, 20 healthy right-handed participants were recruited and randomly assigned to BCI-SRF group or inborn finger group (Finger) for 4-week training and measured by novel SRF-finger opposition sequences and multimodal MRI.

Strongly coordinating mediator enables single-step resource recovery from heavy metal-organic complexes in wastewater.

Heavy metals complexed with organic ligands are among the most critical carcinogens threatening global water safety. The challenge of efficiently and cost-effectively removing and recovering these metals has long eluded existing technologies. Here, we show a strategy of coordinating mediator-based electro-reduction (CMBER) for the single-step recovery of heavy metals from wastewater contaminated with heavy metal-organic complexes.

Trivalent recombinant protein vaccine induces cross-neutralization against XBB lineage and JN.1 subvariants: preclinical and phase 1 clinical trials.

The immune escape capacities of XBB variants necessitate the authorization of vaccines with these antigens. In this study, we produce three recombinant trimeric proteins from the RBD sequences of Delta, BA.5, and XBB.

Colon-targeted engineered postbiotics nanoparticles alleviate osteoporosis through the gut-bone axis.

The potential for mitigating intestinal inflammation through the gut-bone axis in the treatment of osteoporosis is significant. While various gut-derived postbiotics or bacterial metabolites have been created as dietary supplements to prevent or reverse bone loss, their efficacy and safety still need improvement. Herein, a colon-targeted drug delivery system is developed using surface engineering of polyvinyl butyrate nanoparticles by shellac resin to achieve sustained release of postbiotics butyric acid at the colorectal site.