Publications by authors named "Z I Sabry"
Article Synopsis
- * Akt1 kinase activates this phosphorylation code, while protein phosphatase 2A inhibits it, suggesting a balance between activation and repression is crucial for iCM formation.
- * Activation of PC14-3-3 disrupts inhibitory complexes within the nucleus that hinder cardiac gene expression, showcasing how post-translational modifications can influence cell reprogramming.
Article Synopsis
- Scientists found a special code called PC14-3-3 that helps turn regular cells into heart cells, which is super important for heart repair.
- This code is controlled by two proteins: Akt1, which adds things to the code, and PP2A, which takes things away.
- When the PC14-3-3 code is activated, it helps the heart cells form better by changing how other proteins are organized inside the cell.
Although lung disease is the primary clinical outcome in COVID-19 patients, how SARS-CoV-2 induces lung pathology remains elusive. Here we describe a high-throughput platform to generate self-organizing and commensurate human lung buds derived from hESCs cultured on micropatterned substrates. Lung buds resemble human fetal lungs and display proximodistal patterning of alveolar and airway tissue directed by KGF.
View Article and Find Full Text PDFCertain animal species utilize electric fields for communication, hunting and spatial orientation. Freshwater planarians move toward the cathode in a static electric field (cathodic electrotaxis). This planarian behavior was first described by Raymond Pearl more than a century ago.
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