Publications by authors named "Z I Bibi Farouk"
A Novel Newborn Screening Program for Sickle Cell Disease in Nigeria.
Int J Neonatal Screen
September 2024
Article Synopsis
- * The program has screened over 7,500 infants since September 2020, identifying 126 with SCD and 1,546 with sickle cell trait (SCT), with a significant percentage receiving genetic counseling and timely referrals for further care.
- * This initiative demonstrates that a sustainable SCD screening and counseling program can be effectively implemented even in low-income settings, improving outcomes for affected newborns and their families.
Article Synopsis
- - Neurological disorders like Alzheimer's disease and Parkinson's disease affect over 50 million people globally and currently lack effective disease-modifying treatments, leading to a significant crisis in dementia care.
- - Key proteins involved in these diseases—amyloid-beta (Aβ), tau, and alpha-synuclein (α-Syn)—are targets for new immunotherapies designed to promote clearance and protect neurons from damage while alleviating symptoms.
- - Recent advancements in disease-modifying therapies (DMTs) involving anti-Aβ and anti-αSyn monoclonal antibodies are being explored in clinical trials, focusing on improving cellular mechanisms that clear these harmful proteins from the brain.
Background: Hypothermia is an important cause of morbidity and mortality among preterm and low-birth-weight neonates. In resource-constrained settings, limited referral infrastructure and technologies for temperature control potentiate preterm hypothermia. While there is some documentation on point-of-admission hypothermia from single center studies, there are limited multicenter studies on the occurrence of hypothermia among preterm infants in resource-limited-settings.
View Article and Find Full Text PDFBackground: Acute Bilirubin Encephalopathy (ABE) is common in Nigeria. Parents' inability to recognize jaundice and delays in seeking care are significant barriers to its prevention.
Methods: We compared associations of (1) interactive antenatal maternal jaundice instruction with postnatal reinforcement, (2) standard postnatal instruction, and (3) no maternal instruction with the incidence of ABE among 647 jaundice admissions stratified for risk factors identified in initial descriptive analysis.
Background: A birth companion is a simple and low-cost intervention that can improve both maternal and newborn health outcomes. The evidence that birth companionship improves labor outcomes and experiences of care has been available for many years. Global and national policies exist in support of birth companions.
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